Agilent Toxicology Drug Screening in Blood by CE-MSn - a Feasibility Study
Update: 01 October, 2023
This document introduces a feasibility study of a capillary electrophoresis-mass spectrometry (CE-MS) technique for toxicological drug screening in blood samples. The study shows that the Agilent LC/MSD Trap system can detect drugs at levels as low as 20 ng/mL in whole blood, suggesting that it may be a suitable tool for screening whole blood samples for drugs. Additionally, the system's capability of generating MSn data allows reliable identification of detected drugs, suggesting that both screening and identification of drugs can be accomplished in one or two injections using the same instrument system.
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MD5 Checksum: B1AFCEF077A4F0403F8A2E16B0EA7896
Publication date: 02 July, 2012
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Agilent Toxicology Drug Screening in Blood by CE-MSn - a Feasibility Study PDF