Update: 30 September, 2023
This rapid method uses the Agilent 6410 Triple Quadrupole (QQQ) with a cation ion exchange column for the liquid chromatography tandem mass spectrometry (LC/MS/MS) analysis of dairy products for melamine. Milk and milk products are prepared with a simple SPE cleanup method employing the new Agilent SampliQ SCX cartridge. The residue is quantified in the multiple reaction monitoring (MRM ) mode. The selectivity of the QQQ can easily eliminate any matrix interferences that may occur in the separation and provide excellent response. The method provides good results with respect to precision, repeatability, and spiked recovery. The recov- ery of 80 ppb and 50 ppb melamine spikes in milk powder using the external stan- dard calculation is 62.5 and 83.4 percent, respectively, and the RSD is less than 3 percent.
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MD5 Checksum: E63C1DD209DA628D56DE3E658EC0E687
Publication date: 12 June, 2012
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