Agilent Multiresidue Analysis of 301 Pesticides in Food Samples by LC/Triple Quadrupole Mass Spectrometry Manual

Update: 29 September, 2023

An analytical methodology for screening and confirming the presence of 301 pesticides in vegetable samples was developed using the Agilent G6410A Triple Quadrupole Mass Spectrometer (QQQ). Of the 301 compounds, 90% could be identified using this procedure with a limit of detection (LOD) in vegetable matrices of 0.01 mg/kg (ppm) or below, which is the level for baby food and banned substances and is the maximum residue level (MRL) used by the European Union. The analytical performance of the method was evaluated for different types of vegetables (tomato and green pepper), showing little or no matrix effects. Linearity of response over 2 orders of magnitude was demonstrated (r2 > 0.99). The authors of this document are E. Michael Thurman and Imma Ferrer from the Department of Civil, Environmental and Architectural Engineering Center for Environmental Mass Spectrometry at the University of Colorado and Jerry A. Zweigenbaum from Agilent Technologies Inc.


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Publication date: 12 June, 2012

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