Update: 29 September, 2023
An LC/MS/MS method was developed for the qualitative and quantitative measurement of nitrofuran metabolites in chicken and shrimp using the Agilent LC/MSD XCT Ion Trap. The limit of quantitation for all four nitrofurans investigated easily met the specified European Union Minimum Required Performance Level of 1 µg/kg and ranged from 0.125 µg/kg to 0.5 µg/kg. Nitrofuran antibiotics are widely used for the treatment of infectious diseases in cattle, pigs, shrimp, and poultry. Due to their rapid metabolism nitrofuran parent substances are not suitable for monitoring and typically their metabolites are analyzed. A liquid chromatography /mass spectrometry/mass spectrometry (LC/MS/MS) method was developed for the sensitive, qualitative, and quantitative analysis of four derivatized nitrofuran metabolites found in shrimp and poultry.
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MD5 Checksum: 78A9E008362793C5AFC71CDC43455A9B
Publication date: 12 June, 2012
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