Update: 28 September, 2023
The document describes the methods of isolating penicillins from the culture medium of certain fungi and synthesizing other penicillins through semisynthesis or precursor-indicated biosynthesis. Penicillin inhibits the polymerization of murin, which is responsible for the stability of the bacteria's cell wall. Due to the toxicity of many antibacterials, various countries regulate the level of antibacterial residues in agricultural, veterinary, dairy, and meat-based food products. The HPLC analysis in the document demonstrates the separation of four common antibacterial drugs with penicillin-like structure on an SB-C18 reversed phase column.
File format: PDF
Size: -
MD5 Checksum: 08D666202997BCC26824ACAE6326372C
Publication date: 12 June, 2012
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PDF Link: Agilent HPLC Analysis of Antibacterial Drugs with Penicillin-Like Structure Manual PDF