Update: 30 September, 2023
This application note describes a method for analyzing pesticides at the trace level using large-volume injection (LVI) with the Agilent programmable temperature vaporizing (PTV) inlet. With LVI, the detection limit of gas chromatography systems can be improved by one to two orders of magnitude over standard methods that require 1- or 2-microliter injections. An Agilent 6890 Series gas chromatograph (GC), configured with a PTV inlet, an Agilent 6890 Series automatic liquid sampler (ALS), and an Agilent 5973 mass selective detector (MSD), was used for the analysis of pesticides in standards and several food extracts. By making 100-microliter injections, several pesticides could be identified by scanning gas chromatography/mass spectrometry (GC/MS) at the 100 ppt (100 ng/L) level. The PTV inlet tolerated dirty food extracts very well; more than 1,500 microliters of such samples were injected into a single PTV liner. This application note includes recommendations for performing LVI using the PTV/6890/5973 GC/MSD system.
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MD5 Checksum: B841475F53C4750BCC645F2C6DD5C8A6
Publication date: 12 June, 2012
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PDF Link: Agilent Trace Level Pesticide Analysis by GC/MS Using Large-Volume Injection Manual PDF