Update: 30 September, 2023
This Application Note describes a method for the long-term detection of anabolic steroid metabolites in urine using both the Agilent 6890N network GC system with an Agilent 5975B Series GC/MSD and the Agilent 7000 Series Triple Quadrupole GC/MS. Monitoring the sulfate conjugates of these metabolites, instead of the routine glucuronide metabolites, allowed detection of methenolone for a post-administration period that was almost twice as long. This was achieved using GC/MS in SIM mode. Performing the analysis on the Triple Quadrupole GC/MS in SRM mode extends the detection period even further, to almost three times as long as the conventional glucuronide approach.
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MD5 Checksum: D51ADE2ACC9C7EE7F07E883B6B85E02D
Publication date: 12 June, 2012
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PDF Link: Agilent LongTerm Detection of Anabolic Steroid Metabolites in Urine Manual PDF