Agilent Characterization of bacteriophage derived anti-staphylococcal protein (P128) from production to purification using Agilent HPLC-Chip Q-TOFLC/MS system

Update: 30 September, 2023

This application note describes the use of an Agilent HPLC-Chip system coupled to an Agilent Accurate-Mass Q-TOF LC/MS system for analysis of in-process samples of recombinant protein production. Combined with the powerful data processing capabilities of Agilent MassHunter and BioConfirm software, the superior mass accuracy of the HPLC-Chip LC/MS platform enabled identifi cation of impurities during the production process. This type of analysis aids in the assessment of impurities found in protein pharmaceutical at the early phases of product development.


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Publication date: 11 June, 2012

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