Agilent Quantitative Analysis of Vitamin C by Ion Suppression Chromatography Manual

Update: 30 September, 2023

This application note describes the optimization of an ion suppression reversed phase HPLC method to detect L-ascorbic acid, and use of the method in the quantitative determination of the acid in fruit juice. PLRP-S columns were used in this investigation. PLRP-S is a rigid macroporous styrene/divinylbenzene HPLC phase with outstanding chemical and physical stability, and high surface area. This chemical stability permits the use of low pH eluents and ion suppression reversed phase HPLC.


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Publication date: 11 June, 2012

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