Agilent High-Throughput In Vitro ADME Permeability Assays With Agilent RapidFire/MS Systems Permeability Assays handbook
Update: 28 September, 2023
This document describes the application of Agilent RapidFire/MS systems for high-throughput in vitro ADME analysis. Permeability assays such as Caco-2 and PAMPA are used to mimic the absorption of potential drug candidates by human intestinal cells. The Agilent RapidFire High-throughput Mass Spectrometry System, coupled with QQQ or TOF MS, enables rapid sample processing and provides results comparable to traditional LC/MS methods in a fraction of the time, making it a cost-effective and highly productive method for assessing permeability in the drug discovery process.
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MD5 Checksum: 0837DAB05E71D63D9BCA87D61ADB6E80
Publication date: 11 June, 2012
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Agilent High-Throughput In Vitro ADME Permeability Assays With Agilent RapidFire/MS Systems Permeability Assays handbook PDF