Update: 28 September, 2023
CHIRALPAK QN-AX and QD-AX are anion exchanger chiral stationary phases providing specific enantioselectivity for acidic compounds. In this Application Note, we demonstrate that the application of these columns can be extended to supercritical fluid chromatography (SFC) for enantiomer separation of acidic compounds. Using the advantages of the advanced technology of the Agilent 1260 Infinity Analytical SFC system, we were able to assess the influence of a series of parameters such as the mobile phase additives and the flow rate to gain insight into the general approaches for method development and optimization.
File format: PDF
Size: -
MD5 Checksum: 095E4F9EDEDFB3FBEF30C653A92F1419
Publication date: 11 June, 2012
Downloads: -
PDF Link: Agilent Enantiomer separation of acidic compounds Manual PDF