Agilent Simultaneous analysis of antifungals in plasma by SPE with Agilent Bond Elut Plexa an Agilent 1260 Infinity LC/MS/MS Manual

Update: 30 September, 2023

This application note presents the performance of Agilent Bond Elut Plexa multi-compound analysis system for the detection of six systemic antifungal drugs in human plasma. The system includes Agilent Bond Elut Plexa polymeric sorbent, Agilent Pursuit XRsUltra 2.8 Diphenyl column and Agilent 1260 Infinity LC Triple Quadrupole LC/MS. Agilent Bond Elut Plexa delivered extremely clean samples, which was demonstrated by detection down to pg levels. All compounds showed near 100% recovery and a single digit % RSD. Superb linearity was achieved in the calibration curves with R2 ¡ 0.995 for all compounds.


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MD5 Checksum: 19B151F897FC7BC6C6BA0731EEB565C6

Publication date: 11 June, 2012

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PDF Link: Agilent Simultaneous analysis of antifungals in plasma by SPE with Agilent Bond Elut Plexa an Agilent 1260 Infinity LC/MS/MS Manual PDF

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