Agilent Determination of Quinolone Antibiotics in Bovine Liver Using Agilent Bond Elut QuEChERS Kits by LC/MS/MS Manual

Update: 29 September, 2023

This paper presents an analytical method for the determination of 11 quinolone antibiotic residues in bovine liver. The method involves a rapid and efficient pretreatment using Agilent Bond Elut QuEChERS kits, followed by extraction and partitioning, and dispersive solid phase extraction for cleanup. The compounds are then determined using LC-ESI-MS-MS in positive ion MRM mode. The method demonstrates good accuracy and precision, with a limit of quantification significantly lower than the maximum residue limit for quinolones in food producing animals.


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Publication date: 11 June, 2012

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