Agilent Technologies Ultra High Speed High Resolution Separations of Reduced Intact Monoclonal Antibodies with Agilent ZORBAX RRHD Sub-2 m 300 Diphenyl UHPLC Column

Update: 29 September, 2023

Fast separations of intact and reduced monoclonal antibodies (mAbs) were achieved with the use of an Agilent ZORBAX Rapid Resolution High Definition (RRHD) 300 diphenyl reversed-phase column and optimized chromatographic conditions. The unique diphenyl phase and robust rapid resolution high definition column technology, in combination with optimized gradient conditions, provided ultra fast separations and delivered excellent peak shapes demonstrating utility for high throughput mAb charac terizations.

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Publication date: 11 June, 2012

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