Update: 30 September, 2023
This application note describes a method using high resolution accurate mass (HRAM) LC/MS for the quantitation of cystine and related metabolites in white blood cells. Excellent assay performance was achieved for cystine quantitation in white blood cells (WBCs) using the ultra-high resolving power and mass accuracy of an Agilent 6530 Accurate-Mass Q-TOF LC/MS System. Further, related metabolites were successfully identified and quantitatively profiled. The HRAM LC/MS data acquired in this study can be retrospectively analyzed to search for more metabolites and biomarkers without sample re-injection.
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MD5 Checksum: FE020BA38E2BA2B9031CA9766B2D2E5B
Publication date: 11 June, 2012
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