Agilent Comparing HILIC RPLC of Morphine using Agilent ZORBAX RRHD Columns with UHPLC/MS Manual

Update: 29 September, 2023

This application note uses Agilent ZORBAX RRHD columns with UHPLC/MS to compare Morphine’s HILIC and RPLC. Both methods use acetonitrile/ammonium acetate buffer mobile phase for isocratic elution. The results show that HILIC mode allows for more sensitive MS detection due to more efficient spraying and desolvation in the ESI-MS source, as a result of the volatile acetonitrile rich mobile phase used.

---

File format: PDF

Size: -

MD5 Checksum: 044B4E6795AE3C59017E699B0267FE54

Publication date: 08 June, 2012

Downloads: -

PDF Link: Agilent Comparing HILIC RPLC of Morphine using Agilent ZORBAX RRHD Columns with UHPLC/MS Manual PDF