The invention discloses a plant essential oil for preventing and controlling tsutsugamushi disease caused by a new species of Leptotrombidium, which comprises the following components in parts by weight: 2-20 parts of thymol, 1-10 parts of eugenol, 1-10 parts of methyl eugenol, 0-15 parts of apiol, 1-20 parts of cinnamaldehyde, 0.1-2 parts of sanguinarine and 0.1-2 parts of hypericin. According to the characteristics of various plant essential oils, the present invention screens out the optimal proportion for tsutsugamushi disease caused by a new species of Leptotrombidium in chickens;复配由多种植物精油进行复配,并具有非常好的抗菌效果,而 且百里香酚和肉桂醛的质量比为5:1时有显著的 协同增效作用,使药物安全、绿色、高效,无毒副 作用和无抗药性,无残留,无配伍禁忌。