Permeable supports, also known as cell culture inserts, are an essential tool for the study of both anchorage-dependent and independent cell lines. You can use cell culture inserts to: w Produce a cell culture environment that closely resembles an in vivo state w Allow polarized cells to carry out metabolic activities in a more natural manner because the cells feed both apically and basolaterally w Co-culture cells with or without cell-to-cell contact w Design a diversity of experiments using various pore sizes, membrane types, and coatings This selection guide will help you choose the right combination of membrane type, pore size, format, and surface treatment to create a cell culture environment that more closely mimics the in vivo environment you desire.