Agilent Rapid determination of the metabolic stability of pharmaceutical drug candidates by triple quadrupole mass spectrometry Manual
Update: 30 September, 2023
This Application Note describes the rapid development of a MRM method for triple quadrupole mass spectrometry, the rapid development of a liquid chromatography method for high throughput conditions with a 1.8 µm RRHT column, the use of the developed LC/MS MRM method for rapid determina- tion of a metabolic stability profile of a pharmaceutical drug, and the relative quantification of the acquired data to generate the metabolic stability profile.
Brand: Agilent
File format: PDF
Size: 1111 KB
MD5 Checksum: 21D4DF55C0576AC496E7BE2A8805EAFC
Publication date: 02 July, 2012
Downloads: -