Agilent Determination of Pharmaceuticals in Water by SPE LC/MS/MS in Both Positive Negative Ion Modes
Update: 01 October, 2023
This application note describes a method for analyzing pharmaceuticals in water using solid-phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC/MS/MS) in both positive and negative ion modes. Good linearity was observed for analytes from 1 pg to 1 ng on column. Repeatability from six injections of analytes at 5 pg on column showed RSDs below 15%, for all target compounds except for fluoxetine at 23%.
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MD5 Checksum: A5D8929C6F240745821B2D145B7692F3
Publication date: 02 July, 2012
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Agilent Determination of Pharmaceuticals in Water by SPE LC/MS/MS in Both Positive Negative Ion Modes PDF